ID-8

ID-8

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ID-8 (147591-46-6) enhances stem cell proliferation and protects pluripotency in culture.1 Inhibits Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK).2

References/Citations:

1) Miyabayashi et al. (2008), Indole derivatives sustain embryonic stem cell self-renewal in long term culture; Biosci. Biotechnol. Biochem., 72 1242
2) Hasegawa et al. (2012), Wnt signaling orchestration with a small molecule DYRK inhibitor provides long-term xeno-free human pluripotent cell expansion ; Stem Cells Translat. Med., 1 18

CAS:
147591-46-6

Catalog Number:
10-4506

Activity:
DYRK Inhibitor

Chemical Name:
1-(4-Methoxyphenyl)-2-methyl-3-nitro-1H-indol-6-ol

Molecular Weight:
298.29

Molecular Formula:
C16H14N2O4

Solubility:
Soluble in DMSO (up to 10 mg/ml).

Physical Properties:
Solid

Purity:
99%
NMR (Confirms)

Storage Temperature:
-20°

Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.

Shipping Code:
RT