BAY K8644

BAY K8644

  • Sale
  • $250.00

BAY K8644 (71145-03-4) is an L-type Ca2+-channel activator with positive inotropic and vasoconstrictive effects.1-4

References/Citations:

1) Schramm et al. (1983) Novel Dihydropyridines with positive inotropic action through activation of Ca2+ channels; Nature, 303 535
2) Yamamoto et al. (1984) Bay K8644 Differentiates between potential and receptor operated Ca2+ channels; Eur. J. Pharmacol. 102 555
3) Thomas et al. (1985) A dihydropyridine (Bay K 8644) that enhances calcium currents in guinea pig and calf myocardial cells. A new type of positive inotropic agent; Circ. Res., 56 87
4) Shi et al. (2009) Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small molecule compounds; Cell Stem Cell, 3 568

CAS:
71145-03-4

Catalog Number:
10-4518

Activity:
L-type calcium channel activator

Chemical Name:
(±)- Methyl 1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-3-pyridinecarboxylate

Molecular Weight:
356.3

Molecular Formula:
C16H15F3N2O4

Solubility:
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).

Physical Properties:
Yellow solid

Purity:
>98% by TLC

Storage Temperature:
-20°

Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.

Shipping Code:
RT